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Michael W McBurney Selected Research

Sirtuin 1

1/2020Resveratrol Inhibits Neointimal Growth after Arterial Injury in High-Fat-Fed Rodents: The Roles of SIRT1 and AMPK.
10/2018Modulating SIRT1 activity variously affects thymic lymphoma development in mice.
11/2017Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization.
1/2017Reversible modulation of SIRT1 activity in a mouse strain.
1/2015Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria.
5/2014SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism.
3/2014The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome.
1/2014Modulation of tumorigenesis by dietary intervention is not mediated by SIRT1 catalytic activity.
11/2013SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD.
8/2013Silent information regulator 1 protects the brain against cerebral ischemic damage.
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Michael W McBurney Research Topics

Disease

9Neoplasms (Cancer)
10/2018 - 12/2010
5Carcinogenesis
10/2018 - 01/2012
4Chronic Obstructive Pulmonary Disease (COPD)
05/2014 - 08/2010
3Insulin Resistance
01/2020 - 03/2010
3Autoimmune Diseases (Autoimmune Disease)
01/2012 - 10/2008
2Prostatic Intraepithelial Neoplasia
01/2015 - 02/2011
2Prostatic Neoplasms (Prostate Cancer)
01/2015 - 02/2011
2Emphysema
11/2013 - 06/2012
2Wallerian Degeneration
12/2011 - 08/2005
1Hyperplasia
01/2020
1Adenoma (Adenomas)
10/2018
1Lymphoma (Lymphomas)
10/2018
1T-Cell Lymphoma (Lymphoma, T Cell)
10/2018
1Non-alcoholic Fatty Liver Disease
11/2017
1Osteoporosis
03/2015
1Hypogonadism (Hypergonadotropic Hypogonadism)
02/2015
1Pneumonia (Pneumonitis)
05/2014
1Metabolic Syndrome (Dysmetabolic Syndrome X)
03/2014
1Pulmonary Emphysema
11/2013
1Infarction (Infarctions)
08/2013
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
08/2013
1Stroke (Strokes)
08/2013
1Brain Ischemia (Cerebral Ischemia)
08/2013
1Ischemic Stroke
08/2013
1Ischemia
08/2013
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
03/2013
1Ulcerative Colitis
03/2013
1Breast Neoplasms (Breast Cancer)
01/2013
1Neoplasm Metastasis (Metastasis)
01/2013
1Premature Aging
06/2012
1Inflammation (Inflammations)
06/2012
1Overnutrition
01/2012
1Hyperglycemia
12/2011
1Glucose Intolerance
12/2011
1Reperfusion Injury
10/2011
1Neuroblastoma
12/2010
1Embryonal Carcinoma
12/2010
1Atherosclerosis
09/2010
1Malocclusion (Crossbite)
08/2010
1HIV Infections (HIV Infection)
03/2008
1Infections
03/2002

Drug/Important Bio-Agent (IBA)

24Sirtuin 1IBA
01/2020 - 03/2008
11Proteins (Proteins, Gene)FDA Link
10/2018 - 08/2005
6NAD (NADH)IBA
01/2015 - 08/2005
4Histone Deacetylases (Histone Deacetylase)IBA
01/2015 - 01/2012
3ResveratrolIBA
01/2020 - 03/2010
3Insulin (Novolin)FDA Link
01/2020 - 12/2011
3SmokeIBA
05/2014 - 08/2010
2AMP-Activated Protein KinasesIBA
01/2020 - 03/2010
2Glucose (Dextrose)FDA LinkGeneric
01/2019 - 03/2010
2Biological ProductsIBA
10/2018 - 01/2017
2Lysine (L-Lysine)FDA Link
11/2013 - 10/2011
2Nicotinamide-Nucleotide AdenylyltransferaseIBA
12/2011 - 08/2005
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
01/2020
1Neutralizing AntibodiesIBA
01/2019
1methylureaIBA
10/2018
1Anaplastic Lymphoma KinaseIBA
10/2018
1Immune Checkpoint InhibitorsIBA
10/2018
1LipidsIBA
11/2017
1Fatty Acids (Saturated Fatty Acids)IBA
11/2017
1Parathyroid Hormone (Parathormone)IBA
03/2015
1Fibroblast Growth Factor 8IBA
02/2015
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
02/2015
1Phenobarbital (Luminal)FDA Link
01/2015
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2015
1Dietary Fats (Dietary Fat)IBA
01/2014
1Tissue Inhibitor of Metalloproteinase-1IBA
11/2013
1Matrix Metalloproteinases (MMPs)IBA
11/2013
1Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
11/2013
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
11/2013
1sirtinolIBA
08/2013
1AntigensIBA
03/2013
1AutoantibodiesIBA
03/2013
1CarcinogensIBA
01/2013
1SRT1720IBA
06/2012
1Pancreatic Elastase (Elastase)IBA
06/2012
1Nerve Growth Factors (Neurotrophins)IBA
01/2012
1SirtuinsIBA
01/2012
1Streptozocin (Streptozotocin)FDA Link
12/2011
1GAP-43 Protein (GAP 43 Protein)IBA
12/2010
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
12/2010
1BucladesineIBA
12/2010
1Differentiation AntigensIBA
12/2010
1Lovastatin (Mevacor)FDA LinkGeneric
12/2010
1EnzymesIBA
08/2005
1DNA (Deoxyribonucleic Acid)IBA
03/2002

Therapy/Procedure

2Therapeutics
10/2018 - 12/2010
1Immunotherapy
10/2018
1Ligation
08/2013